Endocrine Abstracts

Introduction: First assessment of lung tumors is often performed by imaging combined with biopsy. This is necessary for immunohistochemical tumor typing, evaluation of treatment options and prognosis. It has been shown in literature reviews that Endobronchial ultrasound (EBUS) with fine needle aspiration cytology (FNAC) is not inferior in diagnostic quality, but much less invasive than mediastinoscopy of chest laparotomy (1–3). In this case report we will describe the cut...

Background: Pegvisomant has demonstrated efficacy in attaining IGF1 normalisation in previously uncontrolled acromegalic patients. Improper or less than prescibed use may lead to suboptimal control.Aim: Evaluation of home educational program.Methods: Multicenter Flemish study in seven non-controlled acromegalic outpatients. All patients were trained for daily s.c. pegvisomant injection at home by one single specialist nurse during ...

To estimate the point prevalence of active Cushing’s disease (CD) in Belgium, all endocrinologists were invited to perform a retrospective chart review of the CD patients they had been treating between 1-1-2009 and 31-12-2010.Only patients requiring cortisol lowering therapy because of cortisol excess could be included, such as de novo patients (n=53), previously diagnosed patients with persisting/recurrent disease after pituitary surgery a...

BackgroundCushing’s syndrome due to ectopic ACTH secretion only accounts for 10% of all cases of Cushing’s syndrome and is most often associated with pulmonary neuro-endocrine tumors. Treatment of ectopic ACTH syndrome is predominantly surgical with resection of the tumor. Following resolution of hypercortisolism, previously subclinical Pneumocystis jiroveci infection can become overt due to restored immune response.Clini...

Aims: To identify factors associated with early postpartum weight retention (PPWR) in women with recent gestational diabetes mellitus (GDM).Methods: Multicentric prospective study in women with a recent history of GDM based on the IADPSG criteria at the oral glucose tolerance test (OGTT) 6-16 weeks postpartum. Data obtained from electronic medical records, self-administered questionnaires, clinical examination and blood sample collection were used for th...